Method for treating disorders and diseases treatable with human fibroblast interferon
US7357925B2 · kind B2 · utility
0Cited by
9References
19Claims
0Family size
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Key dates
| Filing date | Aug 28, 2003 |
| Grant date | Apr 15, 2008 |
| Priority date | — |
| Expiry date | Mar 4, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
PEG-IFN-β conjugates, where a PEG moiety is covalently bound to Cys17 of human IFN-β, are produced by a process of site specific PEGylation with a thiol reactive PEGylating agent. A pharmaceutical composition and a method for treating infections, tumors and autoimmune and inflammatory diseases are also provided. The invention further relates to a method for the stepwise attachment of PEG moieties in series to a polypeptide, and more particularly to IFN-β.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.