Diagnostic markers of acute coronary syndrome and methods of use thereof
US7358055B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2005 |
| Grant date | Apr 15, 2008 |
| Priority date | — |
| Expiry date | Aug 17, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/324
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for the diagnosis and evaluation of acute coronary syndromes. In particular, patient test samples are analyzed for the presence and amount of members of a panel of markers comprising one or more specific markers for myocardial injury and one or more non-specific markers for myocardial injury. A variety of markers are disclosed for assembling a panel of markers for such diagnosis and evaluation. In various aspects, the invention provides methods for the early detection and differentiation of stable angina, unstable angina, and myocardial infarction. Invention methods provide rapid, sensitive and specific assays that can greatly increase the number of patients that can receive beneficial treatment and therapy, reduce the costs associated with incorrect diagnosis, and provide important information about the prognosis of the patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.