Immunoregulatory compositions
US7358330B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 7, 2004 |
| Grant date | Apr 15, 2008 |
| Priority date | — |
| Expiry date | Apr 27, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds exhibiting immunoregulatory activity as determined by measuring the compound's ability to modulate production of NO by a cell. Preferred compounds include or consist of a sequenceAAL AAQ AAG AAVwherein AAL is a substituted or unsubstituted non-polar amino acid selected from the group consisting of Ala and Leu; wherein AAQ is a substituted or unsubstituted amino acid selected from the group consisting of Gln, Pro, and Ala; wherein AAG is a substituted or unsubstituted amino acid Gly, and wherein AAV is a substituted or unsubstituted non-polar amino acid selected from the group consisting of Val and Ala. In one embodiment, the compound consists of a tripeptide selected from the group AQG, MTR, VVC, and mixtures thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.