Substituted carboxylic acids
US7358364B2 · kind B2 · utility
1Cited by
11References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 14, 2004 |
| Grant date | Apr 15, 2008 |
| Priority date | — |
| Expiry date | Sep 27, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds and pharmaceutically acceptable salts of formula (I):which are useful in the treatment of metabolic disorders related to insulin resistance or hyperglycemia. These compounds include inhibitors of protein tyrosine phosphatase (PTP-1B) that are useful in the treatment of diabetes and other PTP-1B mediated diseases, such as cancer, neurodegenerative diseases and the like. The compounds of the invention are also useful in pharmaceutical compositions and methods of treating the aforementioned conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.