Cytotoxic CD44 antibody immunoconjugates

US7361347B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Guenther Adolf · Wien, AT
• Erik Patzelt · Purkersdorf, AT
• Marlies Sproll · Gauting, DE
• Karl-Heinz Heider · Stockerau, AT

Key dates

• Filing date: Jul 1, 2005
• Grant date: Apr 22, 2008
• Expiry date: Nov 30, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/68033
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel conjugates of CD44 antibodies with cytotoxic compounds, pharmaceutical compositions comprising such compounds, and their use in tumor therapy.