Safe mutant viral vaccines
US7361357B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 16, 2004 |
| Grant date | Apr 22, 2008 |
| Priority date | — |
| Expiry date | Nov 4, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/24334
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides safe vaccines and methods of preparing such vaccines. The vaccines of the present invention contain at least two live mutant viruses of the same family or nucleic acid molecules encoding such viruses, wherein each of the two viruses or the encoding nucleic adds contains a mutation that confers a desirable phenotype and the mutations in the viruses reside in the same genomic site such that the mutant viruses cannot recombine with each other to eliminate the mutations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.