Approach to molecular diagnosis of human papillomavirus-related diseases
US7361460B2 · kind B2 · utility
13Cited by
5References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 11, 2003 |
| Grant date | Apr 22, 2008 |
| Priority date | — |
| Expiry date | Jun 24, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/708
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to an accurate, sensitive, and efficient sequential or concurrently sequential method for molecular diagnosis of human papillomavirus (HPV)-based disease, where the method improves the accuracy and reliability of diagnostic and prognostic assessments of HPV-based disease. The method of the invention comprises a primary screen of a sample for HPV nucleic acids, followed by a secondary screen for molecular markers, such as proliferation and cell cycle control group protein markers. The sequential or concurrently sequential method significantly reduces the number of false positive results.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.