Method, systems and kits for immuno-detection of epitopes expressed on molecules

US7361464B2 · kind B2 · utility

Assignee

• The Trustees of the University of Pennsylvania · US

Inventors

• Mark I. Greene · Levittown, US
• James Eberwine · Philadelphia, US
• Janet Kacharmina · Davis, US
• Hongtao Zhang · Zhaocheng, CN

Key dates

• Filing date: May 28, 2004
• Grant date: Apr 22, 2008
• Expiry date: Jun 10, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/565
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods, systems and kits are provided for detecting molecules expressing a selected epitope in a sample through use of an epitope detector containing a single chain Fv for the selected epitope or a constrained epitope specific.CDR attached to an oligonucleotide.