Compositions and methods relating to colon specific genes and proteins
US7361475B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 25, 2005 |
| Grant date | Apr 22, 2008 |
| Priority date | — |
| Expiry date | Jan 9, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic colon cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating colon cancer and non-cancerous disease states in colon tissue, identifying colon tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered colon tissue for treatment and research.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.