Stable lipid-comprising drug delivery complexes and methods for their production
US7361640B2 · kind B2 · utility
9Cited by
104References
81Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 29, 2003 |
| Grant date | Apr 22, 2008 |
| Priority date | — |
| Expiry date | Apr 29, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1272
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the prior art admixture method and upon purification, the complexes produced by the method of this invention are 50 to 500 fold more concentrated than the complexes formed by admixture. The method described herein provides for the large scale production of lipid-comprising drug delivery systems useful for gene therapy and other applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.