Dilution resistant viscoelastic compositions
US7363928B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 30, 2004 |
| Grant date | Apr 29, 2008 |
| Priority date | — |
| Expiry date | May 20, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of performing intra-articular therapy and a dilution resistant viscoelastic composition are disclosed. One embodiment of the dilution resistant composition comprises a hyaluronate-based viscoelastic agent and a low viscosity, polymer-containing solution. The hyaluronate-based viscoelastic can be an aqueous solution sodium hyaluronate having an average molecular weight greater than 750,000 Daltons and a concentration by weight between 0.5% and 3%. The polymer-containing solution can contain a polymer selected from the group consisting of chondroitin sulfate and hydroxypropylmethylcellulose. One embodiment can comprise a polymer-containing solution containing hydroxypropylmethylcellulose at a concentration by weight from about 0.05% to about 5.0% and chondroitin sulfate at a concentration by weight from about 0.1 to about 7%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.