Solid dispersion pharamaceutical formulations
US7364752B1 · kind B1 · utility
14Cited by
81References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 10, 2000 |
| Grant date | Apr 29, 2008 |
| Priority date | — |
| Expiry date | Sep 29, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition is disclosed which comprises a solid dispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved dissolution properties. The solid dispersion may optionally be encapsulated in hard gelatin capsules, compressed into a tablet, or may be granulated with a pharmaceutically acceptable granulating agent. Also disclosed are methods of making said solid dispersion and methods of treating an HIV infection employing said solid dispersion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.