Pharmaceutical use of Graptopetalum and related plants
US7364758B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Aug 31, 2004 |
| Grant date | Apr 29, 2008 |
| Priority date | — |
| Expiry date | Oct 28, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions comprising Graptopetalum and uses thereof Graptopetalum can protect animals from liver diseases and medical conditions, such as inflammation, steatosis, and fibrosis. In particular, Graptopetalum inhibits proliferation of activated hepatic stellate cells, which play a pivotal role in liver fibrosis. Graptopetalum also has anti-fibrosis activities as well as inhibits proliferation of lung fibroblasts. Therefore, in addition to being a prophylactic and therapeutic agent for the liver, Graptopetalum is useful against fibrosis or inflammation of tissues or organs other than the liver, in particular lung, kidney, and bladder. Other plants in the family of Crassulaceae, particularly Echeveria, have similar effects as Graptopetalum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.