Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them

US7365064B2 · kind B2 · utility

Assignee

• DR. REDDY'S LABORATORIES LIMITED · IN

Inventors

• Debnath Bhuniya · Pune, IN
• Saibal Kumar Das · Hyderabad, IN
• Gurram Ranga Madhavan · Hyderabad, IN
• Javed Iqbal · Hyderabad, IN
• Ranjan Chakrabarti · Hyderabad, IN

Key dates

• Filing date: Oct 15, 2002
• Grant date: Apr 29, 2008
• Expiry date: Jul 30, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D279/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I) their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them, to a process for preparing such compounds. More particularly, the present invention relates to novel alkyl carboxylic acids of the general, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them, to a process for preparing such compounds. The present invention also relates to processes for the preparation of the compounds of formula (I), novel intermediates, processes for their preparation, their use in the preparation of the above said compounds and their use as antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds