N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines

US7365082B2 · kind B2 · utility

Assignee

• BAYER CROPSCIENCE AKTIENGESELLSCHAFT · DE

Inventors

• Ping Ding · Lawrenceville, US
• Robert N. Henrie, II · Pennington, US
• Daniel H. Cohen · Princeton, US
• John W. Lyga · Berkeley Heights, US
• David Rosen · Kendall Park, US
• George Theodoridis · Princeton, US
• Qun Zhang · Nanhu, CN
• Walter H. Yeager · Yardley, US
• Stephen Donovan · Santa Ana, US
• Steven Zhang · Newton, US
• Inna Shulman · Langhorne, US
• Seong Jae Yu · Pennington, US
• Guozhi Wang · Beijing, CN
• Y. Larry Zhang · Kendall Park, US
• Ariamala Gopalsamy · Lexington, US
• Dennis L. Warkentin · Plainsboro, US
• Paul E. Rensner · Yardley, US
• Ian R. Silverman · Maple Shade, US
• Thomas G. Cullen · Milltown, US

Key dates

• Filing date: Dec 8, 2003
• Grant date: Apr 29, 2008
• Expiry date: Dec 8, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is CH or N; and B, D, E, R, R1, R2, R3, R4, R5, R6, R7 and R8 are fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.