MRI contrast agents
US7368099B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 3, 2004 |
| Grant date | May 6, 2008 |
| Priority date | — |
| Expiry date | Feb 3, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An MRI contrast agent enables direct detection and imaging of exfoliated vascular endothelial sites. The MRI contrast agent includes an imaging unit which contains an unpaired electron-carrying atom and/or molecule and is capable of amplifying or reducing MRI signals, and a detection unit which is bonded to the imaging unit and is capable of selectively recognizing exfoliated vascular endothelial sites and binding thereto. The detection unit is exemplified by one having a chemical structure expressed by the following formula (I), wherein at least one of R1-R11 is, for example, a sulfonic acid group, and X is, for example, a phenyl group which may be substituted:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.