S. aureus fibrinogen binding protein gene

US7368112B2 · kind B2 · utility

Assignee

• THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN · IE

Inventors

• Timothy J. Foster · Dublin, IE
• Damien McDevitt · Berwyn, US

Key dates

• Filing date: Feb 7, 2006
• Grant date: May 6, 2008
• Expiry date: Feb 7, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/76
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The isolation of genes and proteins from Staphylococcus aureus is provided, and the nucleic acids coding for specific regions of the S. aureus CIfA protein are described. The nucleic acids encode proteins that can be useful as vaccines or in pharmaceutical compositions for application to prevent infection, promotion of wound healing, blocking adherence to indwelling medical devices, or diagnosis of infection.