Patent · US Expired

Polymerase chain reaction using metallic glass-coated microwire

US7368166B2 · kind B2 · utility

1Cited by
4References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 4, 2005
Grant dateMay 6, 2008
Priority date
Expiry dateApr 28, 2025

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/2958
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A metallic glass-coated microwire has controllable surface porosity. The porosity is achieved by etching the metallic glass-coated microwire or other shapes of glass-coated bodies with acid after annealing to produce a multi-phase glass coating. Porous metallic glass-coated microwires are found to make superior PCR machines, which find use in a variety of in vivo, biochemical, and chemical sensors. Advantageously, the PCR apparatus is smaller, less expensive to construct than conventional units. It readily carries out in vivo passive or active operations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.