Diagnostic assay for transmissible spongiform encephalopathies
US7368247B2 · kind B2 · utility
3Cited by
0References
9Claims
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Key dates
| Filing date | Sep 10, 2002 |
| Grant date | May 6, 2008 |
| Priority date | — |
| Expiry date | Oct 10, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/106664
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Heart and brain fatty acid binding proteins (H-FABP, B-FABP) are markers for TSEs, especially CJD. The invention provides a diagnostic assay for either of these markers, preferably by enzyme immunoassay using a specific antibody thereto. Since H-FABP is also a marker for acute myocardial infarction (AMI), to distinguish CJD from AMI requires an assay specific to AMI, e.g. using troponin-1 or CK-MB as a marker, also to be carried out.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.