Patent · US Expired

Eukaryotic cell division genes and their use in diagnosis and treatment of proliferative diseases

US7368248B2 · kind B2 · utility

0Cited by

3References

2Claims

0Family size

Assignee

Cenix Bioscience GmbH · DE

Inventors

Christophe Echeverri · Dresden, DE
Pierre Goenczy · Lausanne, CH
Anthony Hyman · Dresden, DE
Steven Jones · West Chester, US
Karen Oegema · Village of La Jolla, US
Matthew Kirkham · Midland, AU

Key dates

Filing date	Nov 9, 2001
Grant date	May 6, 2008
Priority date	—
Expiry date	Mar 22, 2023

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in cell division and proliferation processes that could be identified by means of RNA-medicated interference (RNAi) and to the identification and isolation of functional orthologues of said genes including all biologically-active derivatives thereof. The invention further relates to the use of said gene products (including said orthologues) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.