Method and device for identifying substances capable of modulating adipocyte differentiation
US7368286B2 · kind B2 · utility
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26Claims
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Assignee
Inventor
Key dates
| Filing date | Jan 17, 2003 |
| Grant date | May 6, 2008 |
| Priority date | — |
| Expiry date | Mar 10, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention concerns a method for identifying compounds capable of modulating adipocyte differentiation, which consists in contacting a compound to be tested with genetically modified pre-adipocyte cells overexpressing the REV-ERB ALPHA receptor and measuring the adipocyte differentiation of said genetically modified cells as compared with the adipocyte differentiation of same said genetically modified pre-adipocyte cells in the absence of said compound to be tested.The invention also concerns genetically modified pre-adipocyte cells overexpressing the REV-ERB ALPHA receptor as well as the method for preparing said cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.