Peptides and methods for the control of obesity
US7368433B2 · kind B2 · utility
10Cited by
11References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 8, 2005 |
| Grant date | May 6, 2008 |
| Priority date | — |
| Expiry date | Nov 8, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention provides novel peptides for use in treating mammals to control appetite and obesity. Disclosed is a peptide derivative having the formula:X1-Z-Q-arg-trp-NH2wherein: X1 is an acyl group, Z is amino-2-naphthyl-carboxylic acid or histidine, Q is (D)phenylalanine or p-iodo-(D)phenylalanine, or a pharmacologically acceptable salt, complex or derivative thereof, the peptide derivative having melanocortin-4 receptor agonist activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.