Metalloproteinase inhibitors

US7368465B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Anders Eriksson · Lund, SE
• Matti Lepisto · Lund, SE
• Michael Lundkvist · Lund, SE
• Magnus Munck Af Rosenschöld · Mölndal, SE
• Pavol Zlatoidsky · Mölndal, SE

Key dates

• Filing date: Mar 13, 2002
• Grant date: May 6, 2008
• Expiry date: Dec 7, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I) wherein Z is SO2(N6) or N(R7)SO2 or N(R7)SO2N(R6) useful as metalloproteinase inhibitors, especially as inhibitors of MMP12.