Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events

US7368469B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Bernward Scholkens · Kelkheim, DE
• Norbert Bender · Nuremberg, DE
• Badrudin Rangoonwala · Hofheim, DE
• Gilles Dagenais · Summerside, CA
• Hertzel Gerstein · Toronto, CA
• Salim Yusuf · Carlisle, CA

Key dates

• Filing date: Jul 21, 2006
• Grant date: May 6, 2008
• Expiry date: Jul 21, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Use of an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with another antihypertensive, a cholesterol lowering agent, a diuretic or aspirin, in the manufacture of a medicament for the prevention of cardiovascular events; a method of preventing cardiovascular events comprising administering to a patient in need of such prevention an effective amount of an inhibitor of the renin angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with another antihypertensive, a cholesterol lowering agent, a diuretic or aspirin; and a combination product containing an an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof and a cholesterol lowering agent.