Constructs for delivery of therapeutic agents to neuronal cells
US7368532B2 · kind B2 · utility
10Cited by
6References
8Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 4, 2000 |
| Grant date | May 6, 2008 |
| Priority date | — |
| Expiry date | May 16, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-toxic polypeptide, for delivery of a therapeutic agent to a neuronal cell, comprises a binding domain that binds to the neuronal cell, and a translocation domain that translocates the therapeutic agent into the neuronal cell, wherein the translocation domain is not a HN domain of a clostridial toxin and is not a fragment or derivative of a HN domain of a clostridial toxin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.