Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them

US7368582B2 · kind B2 · utility

Assignee

• Solvay Pharmaceuticals, GmbH · US

Inventors

• David Sykes · Boston, US
• Brian Moloney · Biggenden, AU
• Lester Marrison · Biggenden, AU
• Dieter Ziegler · Hemmingen, DE
• Michael Mlinaric · Hannover, DE
• Christiane Boecker · Hannover, DE
• Reinhard Brueckner · Hannover, DE
• Michael Weske · Burgdorf, DE
• Klaus Witte · Hannover, DE
• Yvan Fischer · Barsinghausen, DE

Key dates

• Filing date: Oct 12, 2004
• Grant date: May 6, 2008
• Expiry date: Jun 24, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D311/68
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds corresponding to formula I:in which R1, R2, R3, R4, R5 and R6 have the meanings given in the description; a process for the preparation of these compounds; intermediate products used to prepare such compounds, and pharmaceutical compositions containing such compounds.