Estrogen receptor α regulated gene expression, related assays and therapeutics
US7371207B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2003 |
| Grant date | May 13, 2008 |
| Priority date | — |
| Expiry date | Apr 10, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A plurality of genes modulated by estrogen or other agents, such as hormones or combinations of hormones, in various types of tissue is described. One embodiment of the disclosure relates to a plurality of genes, which demonstrates certain patterns of expression differing qualitatively or quantitatively, with and without exposure to estrogen and/or other hormone compositions. Methods of using these genes in identifying candidate agents that exert at least some of the biological effects of estrogen and/or other hormone, and pharmaceuticals and related therapies also is disclosed. The use of the plurality of genes in methods of monitoring, in gene chips and in kits also is disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.