Substituted azaporphyrins as fluorescence labels
US7371524B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2004 |
| Grant date | May 13, 2008 |
| Priority date | — |
| Expiry date | Aug 31, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/968
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to marker components, fluorescent probes, oligonucleotides, hybridization assays, and immunoassays using such products, and methods for making such products. According to the present invention, detectably labeled marker components are provided that comprise a fluorescent moiety coupled to two small solubilizing groups, one on each side of the molecular plane, said fluorescent moiety having substituents to control net charge so as to reduce or remove the problems of solvent sensitivity and nonspecific binding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.