Patent · US Expired

2-butanol production method

US7371903B2 · kind B2 · utility

6Cited by

2References

19Claims

0Family size

Assignee

IEP GMBH · US

Inventors

Antje Gupta · Wiesbaden, DE
Anke Tschentscher · Eltville am Rhein, DE
Maria Bobkova · Idstein, DE

Key dates

Filing date	Apr 29, 2005
Grant date	May 13, 2008
Priority date	—
Expiry date	Apr 29, 2025

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02E50/10
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to a process for the preparation of 2-butanol by enzymatic-catalyzed reduction of 2-butanone with a carbonyl reductase and a coenzyme and is characterized in that an aqueous phase, which contains the carbonyl reductase and the coenzyme, is contacted with an alcoholic phase, which is not miscible with the aqueous phase and contains 2-butanone, in order to reduce the 2-butanone, with the proviso that the alcohol present in the alcoholic phase is a secondary alcohol capable of regenerating the coenzyme and exhibiting a boiling point which lies above that of water, whereupon the 2-butanol formed is separated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.