Methods of analysis of degraded nucleic acid samples
US7374927B2 · kind B2 · utility
49Cited by
4References
4Claims
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Key dates
| Filing date | May 3, 2005 |
| Grant date | May 20, 2008 |
| Priority date | — |
| Expiry date | Sep 13, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/166
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides arrays for analysis of compromised nucleic acid samples, for example, nucleic acids obtained from formalin fixed paraffin embedded samples and methods to analyzed these compromised samples. Arrays are disclosed in which the probe selection region used to select probes for the array is the 300 bases of the target MRNA that are immediately upstream of the start of the poly(A) tail of the mRNA. The probes selected for the array are more biased toward the 3′ end of the mRNA than other arrays that are currently available.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.