Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof

US7375090B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Frank Himmelsbach · Mittelbiberach, DE
• Peter Eickelmann · Mittelbiberach, DE
• Leo Thomas · Biberach, DE
• Edward Barsoumian · Toyonaka, JP

Key dates

• Filing date: Aug 24, 2004
• Grant date: May 20, 2008
• Expiry date: Oct 10, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H17/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to glucopyranosyloxy-pyrazoles of general formulawhereinR1 to R6 and R7a, R7b, R7c are defined as in claim 1, the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological properties, particularly an inhibitory effect on sodium-dependent glucose cotransporter SGLT, the use thereof for the treatment of diseases, particularly metabolic disorders such as diabetes, and the preparation thereof.