Increasing ATP availability by inhibition of creatine kinase (CK) leakage resulting from high-intensity exercise
US7375097B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Aug 30, 2006 |
| Grant date | May 20, 2008 |
| Priority date | — |
| Expiry date | Aug 30, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/66
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method of increasing Adenosine Triphosphate levels in a mammal wherein 2-(carbamimidoyl-methyl-amino)ethoxyphosphonic acid inhibits the leakage of the Adenosine Triphosphate-dependant enzyme Creatine Kinase. Via the inhibition of Creatine Kinase leakage, Adenosine Triphosphate is not utilized in the conversion of creatine to phosphocreatine, thereby making it available for use in muscular contractions. The increase in availability leads to longer endurance and more forceful muscular contractions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.