NF-κB inhibitors
US7375131B2 · kind B2 · utility
2Cited by
12References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 29, 2003 |
| Grant date | May 20, 2008 |
| Priority date | — |
| Expiry date | Feb 19, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.