Protein compatible methods and compounds for controlling the morphology and shrinkage of silica derived from polyol-modified silanes
US7375168B2 · kind B2 · utility
13Cited by
22References
74Claims
0Family size
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Key dates
| Filing date | Apr 1, 2004 |
| Grant date | May 20, 2008 |
| Priority date | — |
| Expiry date | Apr 1, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/528
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Siliceous materials were prepared by adding one or more additives, including one or more water soluble polymers, and derivatives thereof, as well as trifunctional silanes, to sols containing tetraalkoxysilanes derived from polyols. The polymers facilitate phase separation of the growing silica gel matrix, leading to high surface area self-supporting silica gels with cure occurring at ambient temperatures. The materials also show a significant reduction in shrinkage properties and significant protein stabilization abilities.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.