Methods of producing C-aryl glucoside SGLT2 inhibitors

US7375213B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Prashant P. Deshpande · Princeton, US
• Bruce A. Ellsworth · Princeton, US
• Janak Singh · Lawrenceville, US
• Theodor Denzel
• Chiajen Lai · Livermore, US
• Gerard Crispino · Princeton, US
• Michael E. Randazzo · Tampa, US
• Jack Z. Gougoutas · Princeton, US

Key dates

• Filing date: Dec 23, 2003
• Grant date: May 20, 2008
• Expiry date: Jul 10, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H15/207
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.