Pyrrolizine compounds useful as anti-inflammatory agents

US7375237B2 · kind B2 · utility

Assignees

• Bristol-Myers Squibb Company · US
• Cerep SA · FR

Inventors

• T. G. Murali Dhar · Newtown, US
• Dharmpal S. Dodd · Princeton, US
• Dominique Potin · Talant, FR
• Michele Launay · Rueil-Malmaison, FR

Key dates

• Filing date: Aug 18, 2005
• Grant date: May 20, 2008
• Expiry date: May 18, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/407
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pyrrolizine compounds having the formula (I),or pharmaceutically-acceptable salts thereof, are effective in treating inflammatory or immune diseases, where A is a four- to seven-membered saturated ring, K is O or S, and R1, R2, R3 n, and M are defined in the specification.