Anti-viral nucleosides
US7378402B2 · kind B2 · utility
38Cited by
7References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 22, 2005 |
| Grant date | May 27, 2008 |
| Priority date | — |
| Expiry date | Apr 10, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one (I:R1=R2=R3=R4=H) and prodrugs thereof are hepatitis C(HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting HCV and treating HCV-mediated diseases, processes for making the compounds and synthetic intermediates employed in the process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.