Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity

US7378409B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Percy H. Carter · Princeton, US
• Robert J. Cherney · Newark, US
• Douglas G. Batt · Wilmington, US
• Gregory D. Brown · Lansdale, US
• John V. Duncia · Newtown, US
• Daniel S. Gardner · Furlong, US
• Michael G. Yang · Narberth, US

Key dates

• Filing date: Aug 19, 2004
• Grant date: May 27, 2008
• Expiry date: Feb 24, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present application describes modulators of MCP-1 of formula (I):or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, artherosclerosis, and rheumatoid arthritis.