Anti-infective agents

US7378414B2 · kind B2 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Douglas K. Hutchinson · Antioch, US
• John Bellettini · Waukegan, US
• David A. Betebenner · Lawrenceville, US
• Richard D. Bishop · Third Lake, US
• Thomas B. Borchardt · Kenosha, US
• Todd D. Bosse · Chicago, US
• Russell D. Cink · Grayslake, US
• Charles A. Flentge · Salem, US
• Bradley D. Gates · Mount Prospect, US
• Brian E. Green · Wonder Lake, US
• Mira Hinman · Libertyville, US
• Peggy P. Huang · Lake Bluff, US
• Larry L. Klein · Lake Forest, US
• Allan C. Krueger · Gurnee, US
• Daniel P. Larson · Highland Park, US
• M. Robert Leanna · Grayslake, US
• Dachun Liu · Vernon Hills, US
• Darold L. Madigan · Elk Grove Village, US
• Keith F. McDaniel · Wauconda, US
• John T. Randolph · Libertyville, US
• Todd W. Rockway · Gurnee, US
• Teresa A. Rosenberg · Gurnee, US
• Kent D. Stewart · Gurnee, US
• Vincent S. Stoll · Libertyville, US
• Rolf Wagner · Antioch, US
• Ming C. Yeung · Grayslake, US

Key dates

• Filing date: Aug 24, 2004
• Grant date: May 27, 2008
• Expiry date: Jun 22, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having the formulaare hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.