Analogues of lipid mediators derived from omega-3 PUFAs and methods of use
US7378444B2 · kind B2 · utility
17Cited by
2References
9Claims
0Family size
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Key dates
| Filing date | Jun 13, 2003 |
| Grant date | May 27, 2008 |
| Priority date | — |
| Expiry date | Jul 21, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C235/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds that are analogues of lipid mediators derived from a fish oil-derived fatty acid, eicosapentaenoic acid [C20:5 ω-3; EPA], but with a longer tissue half-life and enhanced bioactivity. These analogues may be used to treat inflammatory, angioproliferative, cardiovascular, thrombophlebotic, vascular, ocular, dermatologic, neurodegenerative, pulmonary, endocrine, reproductive, rheumatologic and gastrointestinal diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.