Method and nucleic acids for the differentiation of prostate tumors

US7381808B2 · kind B2 · utility

Assignee

• EPIGENOMICS AG · DE

Inventors

• Juergen Distler · Berlin, DE
• Fabian Model · Berlin, DE
• Peter Adorjan · Berlin, DE

Key dates

• Filing date: Jun 13, 2002
• Grant date: Jun 3, 2008
• Expiry date: Jun 13, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C40B40/06
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to chemically modified genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for use in characterisation, classification, differentiation, diagnosis and therapy of prostate lesions.