Fluorescence-mediated molecular tomography
US7383076B2 · kind B2 · utility
55Cited by
23References
65Claims
0Family size
Assignee
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Key dates
| Filing date | May 22, 2003 |
| Grant date | Jun 3, 2008 |
| Priority date | — |
| Expiry date | Sep 10, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6484
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to a fluorescence-mediated molecular tomographic imaging system, designed to detect near-infrared fluorescence activation in deep tissues. The system can use targeted fluorescent molecular probes or highly sensitive activatable fluorescence molecular probes. Such probes add molecular specificity and yield high fluorescence contrast, to allow early detection and molecular target assessment of diseased tissue, such as cancers, in vivo. The new tomographic imaging system enables three-dimensional localization in deep tissues and quantitation of molecular probes.
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