Compositions capable of inhibiting reactive oxygen and carbonyl species

US7384558B2 · kind B2 · utility

Assignees

• Baxter International Inc. · US
• Baxter Healthcare SA · CH

Inventors

• Ton That Hai · Round Lake, US
• Mark Nordhaus · Antioch, US
• Paul Sanders · Greendale, US
• Cong Jiang · Gurnee, US
• Sujatha Karoor · Lake Forest, US
• Ben Melnick · Chicago, US
• Leo Martis · Long Grove, US

Key dates

• Filing date: Jul 26, 2004
• Grant date: Jun 10, 2008
• Expiry date: Jan 12, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P39/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Therapeutic compositions are provided. The compositions include a single molecule that can display both antioxidant and carbonyl trapping properties. This can effectively reduce inflammation, oxidative stress and carbonyl stress, such as to prevent and/or treat cardiovascular disease and inflammatory diseases in kidney disease patients.