Method for producing salts of tolperisone
US7385060B2 · kind B2 · utility
4Cited by
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6Claims
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Assignee
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Key dates
| Filing date | Mar 31, 2003 |
| Grant date | Jun 10, 2008 |
| Priority date | — |
| Expiry date | Sep 6, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/108
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a method for producing an addition salt of 2,4′-dimethyl-3-piperidino-propiophenone (tolperisone) with a pharmaceutically acceptable acid, of formula (I). According to the invention, 4-methylpropiophenone is reacted with piperidine hydrochloride and 1,2-dioxolane in the presence of an acid serving as a catalyst, and the tolperisone obtained in the form of an acid addition salt is separated by filtering after the reaction mixture has cooled down
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.