Methods of treating hemophilia or von willebrand disease with p-selectin
US7387777B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 19, 2004 |
| Grant date | Jun 17, 2008 |
| Priority date | — |
| Expiry date | Jul 5, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/70564
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention identifies P-selectin as a modulator of hemostasis. Accordingly, the present invention relates to methods for the identification and use of modulators of P-selectin activity as modulators of hemostasis. The invention also relates to methods and compositions for the diagnosis and treatment of hemostatic disorders, including, but not limited to, hemorrhagic disorders and thrombotic disorders. The present invention describes methods for the diagnostic evaluation and prognosis of various hemostatic conditions, and for the identification of subjects exhibiting a predisposition to such conditions. In addition, the present invention provides methods for the diagnostic monitoring of patients undergoing clinical evaluation for the treatment of a hemostatic or vascular disorders, and for monitoring the efficacy of compounds in clinical trials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.