SN-38 lipid complexes and their methods of use
US7390502B2 · kind B2 · utility
0Cited by
116References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2003 |
| Grant date | Jun 24, 2008 |
| Priority date | — |
| Expiry date | Jul 28, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is for novel compositions and methods for treating diseases caused by cellular proliferation, particularly, for treating cancer in mammals and more particularly in humans. The therapeutic compositions of the present invention include SN-38 lipid complexes in which the complexes can contain any of a variety of neutral or charged lipids and, desirably, cardiolipin. The compositions are capable of efficiently incorporating SN-38 into complexes and are capable of solubilizing relatively high concentrations of SN-38.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.