Carboxamide spirolactam CGRP receptor antagonists
US7390798B2 · kind B2 · utility
31Cited by
0References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 9, 2005 |
| Grant date | Jun 24, 2008 |
| Priority date | — |
| Expiry date | Feb 9, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds of Formula I: I (where variables A1, A2, B, J, K, m, n, R4, R5a, R5b and R5c are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.