Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same
US7393525B2 · kind B2 · utility
24Cited by
18References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 21, 2003 |
| Grant date | Jul 1, 2008 |
| Priority date | — |
| Expiry date | May 9, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said the animal cells with live invasive bacteria, wherein bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.