Detection of specific nitrated markers
US7393649B2 · kind B2 · utility
2Cited by
2References
1Claims
0Family size
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Key dates
| Filing date | Mar 12, 2003 |
| Grant date | Jul 1, 2008 |
| Priority date | — |
| Expiry date | Dec 4, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/173076
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.