Patent · US Expired

Confluence regulated adhesion molecules useful in modulating vascular permeability

US7393651B2 · kind B2 · utility

1Cited by
3References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 30, 2004
Grant dateJul 1, 2008
Priority date
Expiry dateDec 30, 2024

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/582
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to new polypeptide in isolated form belonging to a subfamily of the human Immunoglobulin Superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3 upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.